Relaxaid PM provides an evidence-based combination of melatonin and standardized botanical extracts for improved mental calm, relaxation, and overall sleep quality.
- Melatonin (6 mg) – Supports the onset of sleep and healthy sleep quality by engaging MT1/MT2 melatonin receptors to align circadian timing. Human meta-analyses show melatonin shortens sleep-onset latency and modestly increases total sleep time.
- Saffron extract (25 mg; ~0.3% safranal) – Supports subjective sleep quality, likely via serotonergic and GABAergic pathways associated with safranal/crocins. Recent randomized trials and reviews report improvements in validated sleep-quality scales in adults with poor sleep.
- Ashwagandha root extract (450 mg; 5% withanolides) Supports sleep quality and efficiency by promoting a healthy stress response (HPA-axis modulation) and calming GABAergic tone. Pooled RCT data show modest but significant improvements in sleep quality, latency, and efficiency versus placebo.
- Valerian root extract (400 mg; 0.8% valerenic acid) Supports relaxation and healthy sleep quality, plausibly through positive allosteric modulation of GABA-A receptors and inhibition of GABA breakdown.
- Passionflower extract (500 mg; 3.5% flavonoids) Promotes relaxation that can support subjective sleep quality, consistent with GABAergic pathway modulation observed preclinically. Small, double-blind human trials report improved self-rated sleep quality versus placebo.
- Apigenin (100 mg) Supports relaxation pathways by acting as a flavonoid modulator at GABA-A receptor sites (mechanistic evidence), which may help prepare the mind for sleep.*
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.